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Rocuronium Bromide (Zemuron®)

Rocuronium Bromide (Zemuron®)

Non-depolarizing neuromuscular blocker


    Adult & Pediatric (over 16 years of age): 1.0 mg/kg slow administration (30-60 seconds)


    Rocuronium bromide is a non-depolarizing neuromuscular blocking agent with a rapid to intermediate onset depending on dose and intermediate duration. It acts by competing for cholinergic receptors at the motor endplate. Has no analgesic properties and the patient maybe conscious, but unable to communicate by any means. Patients should be pre-medicated with a sedative (versed) as Rocuronium has no effect on patient’s level of consciousness. First muscles affected include eyes, face, neck; followed by limbs, abdomen, chest; diaphragm affected last. Recovery usually occurs in the reverse order and may take longer than 60 minutes. IV onset of actions in less than 2 minutes, peaks in 1-3 minutes and lasts for 20-60 minutes at the dose of 1.0 mg/kg


    Authorized paramedic only may induce general anesthesia to facilitate intubation. It may also be used by a paramedic post intubation during treatment of the patient while using Induced Hypothermia.


    None in cardiac arrest.


    Causes respiratory paralysis; supportive airway control must be continuous and under direct observation at all times. Caution in patients with known significant hepatic disease, pulmonary hypertension and valvular heart disease.


Hypersensitivity reactions are possible.

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